Rory Calhoun starred as Big Bill Longley (Rory Calhoun), a fast gun who wandered the Texas frontier of the 1870s helping those in need.

Friends and acquaintances of Big Bill Longley included:

• Regis Parton as Pete Bray
• Duncan Lamont as David MacMorris
• Alan Hale Jr. as Sculley
• Kem Dibbs as Matt Horton
• Pedro Gonzalez Gonzalez as Pedro Vasquez
• Kipp Hamilton as Steve
• Tom London as Agent
• Alan Dinehart III as Brazos Kid
• Reed Hadley as Wild Jack Tobin
• Chris Alcaide as Deputy Luke Smith
• Andy Clyde as Andy Miles
• Lane Bradford as Buck Tanner
• James Drake as Buck
• Harry Harvey as Clyde Hatbridge
• Denver Pyle as Chip Andrews
• Robert J. Wilke as Asa Kirby
• Ted Adams as Conners
• Mario Alcalde as Yellow Hawk
• Michael Dante as Steve Chambers
• Lita Baron as Dolores
• Chick Bilyeu as Marshal
• Richard Travis as Governor
• Hal Smith as The Bartender
• Howard Negley as Doctor
• Bud Osborne as Stagecoach Driver
• Norman Leavitt as Bender, Hotel Clerk
• Barbara Stuart as Poker Alice

Here are some of Bill's adventures and exploits:

• Tracks a killer to save his friend falsely accused of  murder.
• Forced into a showdown to see who is the fastest gun.
• Encounters a rancher's son whose father taught him to kill.
• Helps a Mexican whose peach orchard is vandalized.
• Hard earned cattle drive money is stolen by bank robbers.
• Helps a Mexican widow meet her husband's prejudice father.
• Helps an alcoholic judge battle a sheriff. who fixes an election
• Tracks his friend's killer who is the son of a respected sheriff.
• Protects a wounded circuit judge so he can get to a trial.
• Must keep a bounty hunter from harming an innocent man.
• Tracks bank robbers who killed a woman and her little girl.
• Searches for the killers of his friend, a photographer.
• Encounters outlaws as he works for the telegraph company.
• Gets involved in a race to herd cattle to Abilene.
• Helps a former marshal find his courage to battle a gang.
• Accidentally gives counterfeit money to buy cattle in Mexico.
• Must face down a gunman hired to kill him.
• Refused help when he brings a wounded man to a ranch.
• Joins a horse race while two men plan to rob a bank.
• Gets involved with two bank robbers pursued by a posse.
• Infiltrates a gang who is counterfeiting silver coins.
• Holds up in a ghost town during a storm and discovers it is filled with outlaws who are friends of the man he is transporting to trial in Colorado.